Impact of 8-week cold-and warm water swimming training combined with cinnamon consumption on serum METRNL, HDAC5, and insulin resistance levels in diabetic male rats.

Objective: Numerous studies have reported the beneficial effects of exercise and the use of herbal supplements in improving type 2 diabetes and insulin resistance. However, there are still many unanswered questions about the effects of cold and hot water, exercise, and herbal supplements on meteorine-like protein (METRNL), which is considered one of the key factors influencing insulin resistance improvement in this condition. Hence, the current study aimed to address these knowledge gaps and investigate the effects of 8 weeks of warm and cold-water swimming exercise with cinnamon consumption on serum levels of METRNL, histone deacetylase-5 (HDAC5), and insulin resistance in diabetic male rats. Methods: For this purpose, 70 diabetic male rats were randomly divided into seven groups (10 rats in each group) H ealthy control (HC) , Diabetic control , swimming training in cold water (temperature 5 °C) , swimming training at 5|| °C + cinnamon consumption (200 mg/kg body weight) , swimming training in warm water (temperature 36-35 °C) , swimming training in warm water (temperature 36-35 °C) + consumption of cinnamon, and consumption of cinnamon only. Results: The present study revealed a significant increase in serum METRNL concentration in the cold-water swimming + cinnamon consumption group (p < 0.05). However, no significant changes were observed in insulin levels and HOMA-IR across the different groups (p > 0.05). Additionally, noteworthy findings included a significant reduction in HDAC5 levels in both the cold-water swimming group and the cold-water swimming + cinnamon consumption group, as well as a significant decrease in fasting blood sugar (FBS) levels in all groups compared to the HC group (p < 0.05). Conclusions: The results of the present study demonstrate that the combination of cold-water swimming exercises and cinnamon extract consumption led to notable increases in serum METRNL concentration. Additionally, significant reductions were observed in HDAC5 and FBS levels. These findings highlight the potential effectiveness and benefits of the combination of cold-water swimming exercises and cinnamon extract consumption as an approach to improve diabetes-related indices.

Effects of swimming training in hot and cold temperatures combined with cinnamon supplementation on HbA1C levels, TBC1D1, and TBC1D4 in diabetic rats.

AIMS: Diabetes is one of the main causes of mortality in developing countries. Performing physical activity in various ways and different environments using herbal supplements can be used as a non-pharmacological solution to prevent and improve diabetes. Hence, this study aimed to investigate the effects of eight weeks of cold water swimming exercise training combined with cinnamon supplementation on HbA1C (Hemoglobin A1c) levels, TBC1D1 (TBC1 domain family member 1), and TBC1D4 (TBC1 Domain Family Member 4) in diabetic rats. MATERIALS AND METHODS: Ninety-one rats (n = 78 diabetic, n = 13 healthy) were divided into seven groups (n = 13 per group): (1) healthy control (HC), (2) diabetic control (DC), (3) swimming training in cold water (5 °C) (S5), (4) swimming training in cold water (5 °C) with a cinnamon supplementation (200 mg/kg body weight) (S5+Ci), (5) swimming training in warm water (36-35 °C) (S35), (6) swimming training in warm water (35-36 °C) with a cinnamon supplementation (S35+Ci), and (7) a cinnamon supplementation only (Ci). To evaluate the hypothesis, a one-way ANOVA and Tukey's post hoc test were used. RESULTS: Findings showed that the TBC1D1 and TBC1D4 levels in the DC and S35 groups were higher than in the HC group (p < 0.001). Also, swimming training in cold water (5 °C) with cinnamon supplementation (S5+Ci) decreased the level of TBC1D1, TBC1D4, HbA1c, and glucose compared to other groups (p < 0.05). CONCLUSIONS: The study revealed that the combination of swimming training in cold water and cinnamon consumption led to a significant reduction in TBC1D1, TBC1D4, and HbA1c. Therefore, this non-traditional exercise approach coupled with cinnamon supplementation can be considered an effective method for improving insulin sensitivity, fasting blood glucose, and HbA1c levels and is proposed as an optimal method to improve glucose indices.

Effects of a 4-week plyometric training on activity patterns during different phases of one-leg drop jump with focus on jump height.

Athletic women have shown a higher risk of ACL injury during jump landing compared to men. Plyometric training can be an alternative way to minimize the risk of knee injuries via the changed muscle activity patterns. Hence, the aim of this study was to determine the effects of a 4-week plyometric training program on the muscle activity pattern in different phases of one-leg drop jump in active girls. Active girls were randomly allocated into 2 groups (Plyometric training = 10, Control group = 10) where the plyometric training group (PTG) performed 60 min exercises, 2 sessions/1 week for 4 weeks while the control group (CG) had their daily activity. In the pre to post test, the sEMG was recorded from the Rectus Femoris (RF), Biceps Femoris (BF), Medial Gastrocnemius (GaM), and Tibialis Anterior (TA) muscles of the dominant leg during the Preparatory phase (PP), Contact Phase (CP), Flight Phase (FP) of one-leg drop jump. Electromyography variables (Signal amplitude, Maximum activity, Time to peak (TTP), Onset and activity time and Order muscle activity) and Ergo jump variables (Time of preparatory phase (TPP), Time of contact phase (TCP), Time of flight (jump height) phase (TFP), and Explosive power were analyzed. The Univariate ANCOVA test showed a significant difference between the two groups in Activity Time, whilst adjusting for pre-test as a Covariate, only in TA muscle (F(1,17) = 5.09, p = 0.038, η2 = 0.230). In PTG. TA (- 15%), GaM (- 19%), and BF muscles (- 9%) started their activity earlier while there was no significant difference between the two groups at the Onset time. TTP of RF was significantly different between the 2 groups only in the PR phase (0.216 ± 0.07 vs 0.153 ± 0.09 s) (p = 0.049, 95% CI = 0.001, 0.127). Results of the present study suggest that a 4-week plyometric training can improve the stability of leg joints via earlier recruitment of muscles and change activity patterns in lower limb muscles. It also recommends that the preparatory phase before landing be considered an important stage in preventing sports injuries in a training program.

Effect of interval and continuous small-sided games training on the bio-motor abilities of young soccer players: a comparative study.

OBJECTIVE: The present study compared the effects of two different small-sided game (SSG) training methods, interval (ISSG) and continuous (CSSG) on the bio-motor abilities of young soccer players. METHODS: Sixteen young soccer players (age: 19.5 ± 0.5 years; height: 177 ± 4.72 cm) were ranked based on the result of a running-based anaerobic sprint test (RAST) and randomly divided into two groups: CSSG (n = 8) and ISSG (n = 8). The training protocols were performed for eight weeks, three sessions per week. Participants were assessed twice (pre- and post-intervention) to estimate their anaerobic capacity with the RAST, aerobic capacity with Yo-Yo intermittent recovery test, body fat percentage with a bioimpedance analysis, speed with a 30-meter run test, and agility with the Illinois agility test. During the training session, the rating of the perceived exertion (RPE) and heart rate (mean and maximum) were recorded to assess the training load. RESULTS: In general, aerobic and anaerobic capacities improved after ISSG (p < 0.05, for all). The between-group analysis with repeated measures ANOVA revealed higher values for ISSG than CSSG groups post-intervention in anaerobic power (p = 0.042, ηp2 = 0.264). In addition, the independent t-test results indicated that ISSG presented lower values of mean heart rate (p = 0.023, effect size [ES] = 0.85) and RPE (p < 0.05, ES = 0.88) than CSSG. Moreover, higher values for maximum heart rate were revealed for ISSG than for the CSSG group (p = 0.004, ES = 0.85). CONCLUSION: In conclusion, the findings of this study suggests that ISSG can lead to better improvements in anaerobic power and aerobic capacity than CSSG. Additionally, the ISSG led to a lower mean heart rate and RPE than the CSSG. Therefore, coaches and trainers may want to consider incorporating ISSG into their training programs for young soccer players to enhance their bio-motor abilities.

Physical activity and nutrition guidelines to help with the fight against COVID-19.

As the world is witnessing the epidemic of coronavirus disease 2019, emerging genetics and clinical pieces of evidence suggest a similar immunopathology to those of severe acute respiratory syndrome and Middle East respiratory syndrome. Staying at home to prevent the spread of the virus and consequently being largely inactive is associated with unintended consequences. These can actually enhance the infection risk and exacerbate poor health conditions including impaired immune function. Physical activity is a feasible way of improving health, particularly physical and mental health in a time of social isolation. However, people with certain health conditions in these circumstances may need a special physical activity programme in addition to any exercise they may already be performing via online programmes. This review aims to provide practical guidelines during the COVID-19 quarantine period. We suggest performing aerobic, resistance training, respiratory muscle training and yoga in the healthy, and in those with upper respiratory tract illness, patients with lower respiratory tract illness should be restricted to respiratory muscle training and yoga. In addition, vitamins D and C, omega-3 fatty acids, and regular consumption of fruit and vegetables might be considered as nutritional aids to support the immune system in those affected by COVID-19.